Look directly above the heads of the audience. You can pretend your speaking to a room of mannequins, but that may or may not freak you out a little. Don't look straight up at the ceiling, but scan the back wall of the room with your eyes. You don't need to make eye-contact with anyone if you can make it look like you are. Pretend you're alone or just talking directly to the Groom. This sounds like it's easier said than done, but it can be pretty simple. Take a few seconds before you start your best man speeches to “get in the zone.” Seriously, take your time. It might feel like a century to you, but time hasn't slowed down. Give your self a quick pep talk. You were chosen out of all the people in the crowd to be the Best Man for the Groom. Be proud of that! There are tons of people who will never get the opportunity to give such a memorable best mans speech to their best friend, father, or son.